Anti-Malarial Drugs Demonstrate Potential in Covid-19 Treatment

 

Anti-Malarial Drugs

Anti-malarial drugs are used in the treatment of malaria. Most antimalarial drugs target the erythrocytic stage of infection that causes symptomatic illness. These include, Atovaquone/Proguanil (Malarone), Chloroquine, Doxycycline, Mefloquine, Primaquine, and Tafenoquine (Arakoda). Chloroquine is the preferred treatment for any parasite. Tropomyosin or thyroxine are used to prepare these drugs. The drugs contain both antimalarials and topical agents for the purpose of alleviating the pain caused by malaria.

High prevalence of malaria around the world is primarily boosting demand for Anti-Malarial Drugs. In 2020 an estimated 241 million cases of malaria occurred worldwide and 627,000 people died, mostly children in sub-Saharan Africa. About 2,000 cases of malaria are diagnosed in the U.S annually. Several companies are focused on approval and launch of new drugs for the treatment of malaria. In May 2020, The U.S. Food and Drug Administration approved artesunate for injection to treat severe malaria in adult and pediatric patients.  Recently, in December 2021, Zydus Cadila, Indian multinational pharmaceutical company, received Orphan Drug Designation for ZY19489 (MMV253), an antimalarial compound.

Various companies are also focused on R&D of new anti-malarial drugs. In December 2019, Ipca Laboratories collaborated with Medicines for Malaria Venture to develop a novel antimalarial co-formulation, Atoguanil, a combination of atovaquone and proguanil. The demand for drugs for the treatment of malaria is significant due to high prevalence of malaria in Africa. According to the World Health Organization, Africa carries a disproportionately high share of the global malaria burden. In 2018, the region was home to 93% of malaria cases and 94% of malaria deaths

Anti-malarial drugs have demonstrated potential in COVID-19 treatment. In December 2021, a Danish laboratory study reported that atovaquone, a part of the antimalarial Malarone, has a protective effect against coronavirus in human lung cells.

Know more about Anti-Malarial drugs- https://bit.ly/3hti2ZT

Comments

Post a Comment

Popular posts from this blog

With the use of High-Frequency alternating current, Radiofrequency Ablation Device convert Electromagnetic Energy into Heat Energy

Image
Radiofrequency Ablation Device RFA is a minimally invasive technique that may be done in a doctor's office or a hospital. The majority of patients are able to return home the same day. RFA can be done with or without minimal sedation. If anaesthesia is utilised, the patient is generally kept awake and alert enough to explain what they are feeling during the nerve stimulation and lesioning. The following are the steps involved in an RFA: ·         On a procedure table, the patient is lying on his or her stomach. An intravenous (IV) line is established if sedation is utilised so that relaxation medication (sedation) can be administered. ·         To reduce the danger of infection, the skin above the treatment region (neck, mid-back, or low back) is thoroughly washed. ·         A numbing drug (anaesthetic) is injected into the location of the RFA injection site to numb a small p...
Read more

The Isocyanates Market to Witness Robust Growth in North America and Asia Pacific

Image
  Organic compounds that contain an isocyanate group are referred to as isocyanates. They are a family of highly reactive, low molecular weight chemicals. Isocyanates are extensively used in the automobile, electronics, and construction industry. Moreover, they are used in a variety of industries using chemicals such as certain coatings/linings, adhesives, lacquers, two pack spray paints, and in foam production such as fillers or insulation. Isocyanates are also used in the production of rigid foams, coatings, elastomers, and adhesives. Increasing demand form the construction industry due to its highly reactive chemical property is expected to be a key factor driving the Isocyanates market growth. Among regions, the Isocyanates M arket is witnessing robust growth in North America and Asia Pacific due to the rapid growth of various end-use industries such as automotive, electronics, and construction, with India, China, and the U.S. being the major growth engines. According to th...
Read more

Air Purifier works as a Sanitizer in the air which helps in reducing pollutants, allergens, and toxins

Image
  Air purifier   Within a confined area, an air purifier eliminates organic and inorganic impurities from the air. The clean air is sent out into the living space after these devices catch pollutants and particles in the air. Dust mites, mould spores, chemicals, poisons, and scents are all trapped by these filters. These gadgets are frequently touted as appropriate tools for asthmatic patients and others who suffer from airborne allergen allergies. An indoor Air purifier ensures the filtering of the air inside a closed room, which it catches and releases as clean air. If the windows may be opened, it functions in addition to the necessary natural ventilation. A contrast must be noted between a professional model and a residential device, since neither provides the same level of air treatment or overall performance. Pollens, fine particles PM2.5 and PM10, VOCs (Volatile Organic Compounds), viruses, and germs are all effectively removed by a professional air purifier with a H...
Read more