Non-Small Cell Lung Cancer; A Disease That Affects Inside And Outside Of Lungs

 

Non-Small Cell Lung Cancer

About 85 percent of lung cancers are Non-Small Cell Lung Cancer (NSCLC), also called large cell carcinoma. This type of cancer starts in the cells that line the inside and outside of the lungs. Doctors determine which type of NSCLC patients have based on how their cancer looks under a microscope and the kind of cells it starts in. Surgical removal of the cancer is the most common treatment for early stage NSCLC.

There are many ways to treat Non-Small Cell Lung Cancer. Some methods use drugs to kill or slow down the growth of the cancer. Other methods involve using the immune system to fight the cancer. Drugs that target a certain cancer cell or a specific molecular change in the cancer are called targeted therapy. These drugs are matched to each tumor after genetic tests. The drugs are taken in pill form or by mouth.

Other types of cancers may be treated with chemotherapy or radiation, which both kill cancer cells. These treatments can help reduce symptoms and improve the ability to breathe. Chemotherapy is the most common treatment for lung cancer and can be very effective. Some people who have non-small cell lung cancer need more than one type of chemotherapy to get the best results. Chemotherapy is a drug that kills cancer cells. It can be given by injection into the vein or by taking a pill that patient can swallow.

Radiation is another treatment option for Non-Small Cell Lung Cancer. It can help shrink the tumor and make it easier to remove with surgery or to cut out. It can also help prevent the cancer from coming back.

Immunotherapy is another treatment option for some people with advanced lung cancer that has spread to other parts of the body. This treatment uses medications called checkpoint inhibitors to boost the immune system so it can attack cancer cells.

Other types of medicines can be used to treat some people with non-small cell lung cancer that has spread to other parts of their bodies or that has recurred (come back). These include monoclonal antibodies and tyrosine kinase inhibitors.

The goal of treatment for most people with Non-Small Cell Lung Cancer is to shrink the tumor and improve the health. The patient may need to have regular check-ups and follow-up tests to see how well the treatment is working. In May 2022, Chugai received regulatory approval from the Ministry of Health, Labor and Welfare of Japan, for its Tecentriq designed to treat NSCLC.

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