Plasmapheresis Device; Used To Remove, Return, or Exchange Blood Plasma or Components

 

Plasmapheresis Device

Plasmapheresis is a procedure in which blood is separated into cells and plasma (liquid). It is the removal, treatment, and return or exchange of blood plasma or components thereof from and to the blood circulation. Plasmapheresis devices are used to collect plasma from human blood and convert it into therapeutic products. These therapeutics are often used to treat a range of diseases and conditions, including autoimmune diseases, hematologic disorders, and renal disorders. Plasmapheresis Devices are also used in plasma donation centers.

Plasmapheresis is a nonsurgical therapy that removes and replaces a patient's blood plasma. It is used as a second-line therapy (after systemic corticosteroids) in the management of central nervous system (CNS) demyelinating diseases (such as neuromyelitis optica, idiopathic optic neuritis, idiopathic transverse myelitis, acute disseminated encephalomyelitis, among others) and multiple sclerosis (MS) relapses (or attacks). This in turn has increased the use or demand for Plasmapheresis Devices around the world.

Plasmapheresis is occasionally used in-patients who are intolerant of high-dose corticosteroids or have medical contraindications to high-dose corticosteroids. Therapeutic plasma exchange is a therapeutic procedure that purifies the blood by removing pathogenic substances from the blood. This procedure is most commonly used in the treatment of autoimmune and hematologic diseases. The process removes large molecular-weight substances from the blood that are not cleared from the blood by conventional hemodialysis or hemofiltration.

Today, Plasmapheresis Device is extensively used to treat Guillain-Barré syndrome, severe myasthenia gravis, Lambert-Eaton syndrome, and chronic demyelinating polyneuropathy. Its effectiveness, however, in other medical conditions such as polymyositis, multiple sclerosis, and dermatomyositis, is still being studied. The U.S. Food and Drug Administration (FDA) has granted 510(k) clearance for the Aurora Xi Plasmapheresis System. The system collects plasma from donated blood and returns the remaining blood components to the donor.

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