Pharmaceutical Drug Delivery; Used to Safely Deliver Pharmaceutical Compounds into the Body

 

Pharmaceutical Drug Delivery

Pharmaceutical Drug Delivery is referred as transfer of a pharmaceutical compound (medicine) into the body for the therapeutic effect (treatment). A novel drug delivery system can be defined as a new approach that uses innovative methods to safely deliver pharmaceutical compounds into the body necessary to achieve desired therapeutic effects (treatment). Slow processing, as well as side effects, of traditional drug therapy are contributing to the emergence of the concept of novel drug delivery systems.

For the treatment of human diseases, nasal and pulmonary routes of drug delivery are gaining increasing importance. Drug delivery refers to the technology utilized to present the drug to the desired body site for the drug release and absorption. Nasal drug delivery has been used as an alternative route for the systemic availability of drugs restricted to intravenous administration. Pharmaceutical Drug Delivery is also used for the treatment of allergic and non-allergic rhinitis, acute treatment of migraine, pain, and nasal congestion associated with common cold, rhinitis, or sinusitis.

Nasal route has shown remarkable advantages that include rapid and high systemic availability, possibility of targeting drugs directly from the nasal cavity to brain, and avoidance of first pass metabolism by the liver. Intranasal drug delivery (or nasal drug delivery) offers a rapid onset of therapeutic effects (local and/or systemic). Pulmonary drug delivery is used to deliver the drug to treat respiratory diseases. Nebulizers, dry powder inhalers, and pressurized metered-dose inhalers are used in pulmonary drug delivery.

The pulmonary route is used to take the drug through the respiratory tract. Pharmaceutical Drug Delivery helps increase the availability of drugs, reduce drug degradation, and prevent harmful side effects of drugs. Moreover, the system enhance drug absorption, efficacy, and the patient experience. However, the development of drugs and medical devices follows well-established paths to make sure that they are safe and effective when they reach the public. Thus, U.S. FDA is speeding up the approval process for drugs and medical devices.

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