Food products can be preserved and made safer using Biopreservation when their microflora is either natural or controlled
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| Biopreservation |
Human Blood, tissues, cells, and organs have the potential
to provide long-term advantages in the treatment of damaged tissues and organs.
Biobanking arose from the awareness that human cells and tissues might be used
for future study and development of new medical methods. Biobanks' primary job
is to collect, process, and store samples and related data. Tissues, cells,
saliva, whole blood, plasma, urine, nucleic acid, organs, and other biological
fluids are stored in biobanks.
The worldwide Biopreservation
Growth development is projected to be hampered by R&D in media solutions
that allow for room temperature storage of biospecimens. Biomatrica, Inc., for
example, supplies DNA stable and RNA stable sample stabilisation medium at room
temperature. Such solutions put a damper on demand for freezers and
refrigerators, limiting the industry's development.
Biopreservation
uses the antibacterial properties of certain microorganisms to prevent rotting
and harmful pathogens from growing in food. This biological technique aims to
reduce the need of chemical additions like nitrite, sodium chloride, and
organic acids in meals. Biopreservation for meat products is still being researched
since it is thought that natural ways of preservation are preferable. The
majority of biopreservation research has focused on lactic acid bacteria's
antagonistic activity against spoilage and pathogenic microorganisms. However,
in the last decade, the use of bacterial viruses (bacteriophages) to eradicate
harmful germs from food has gotten a lot of press.
Types of
Biopreservation-
While a brief analysis of the hMSC regulatory filings to the
FDA in 2015 shows that cryopreservation is the predominant type of
biopreservation in 75% of submissions, there are still over a quarter of
treatments that do not cryopreserve (Mendicino et al., 2014). Many different
types of biopreservation are being studied in order to ensure that the end
product CQAs are kept throughout the production and supply chain process. This
can involve "cell pausing" and/or hypothermic preservation at various
temperatures, such as ambient (Robinson et al., 2014; Hunt et al., 2005; Eidet
et al., 2015) or cold temperatures (Matsumoto et al., 2002; Moce-Llivina, 2004).
Finally, deciding which Biopreservation
approach is best will need considering which method has the least impact on the
product's CQAs while maintaining a viable and realistic supply chain.
Lytic bacteriophages, lactic acid bacteria, and bacteriocins
are examples of biopreservation techniques that have been found to be effective
in preventing microbiological deterioration. For example, according to Li et
al. (2014), the bacteriophage Spp001 is a possible candidate for application in
chilled fish fillet biopreservation since it effectively controls S.
putrefaciens under chilled circumstances. Valeiro et al. did another recent
investigation with highly intriguing results in the field of biopreservation
(2014). These researchers demonstrated that a Lactobacillus brevis-based
bioingredient obtained after growth in a flour-based medium could represent an
innovative strategy in industrial bread production to obtain acidified
yeast-leavened products, reducing the negative effects of bran addition and
preventing ropy spoilage.

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