Bone Graft Substitutes is an excellent way of treating damaged or missing bone

 

Bone Graft Substitutes

Bone Grafting is a medical procedure in which the replacement of missing bone is performed. Ceramics, polymers, and bioactive glass are some of the bone grafting solutions. There are several types of bone graft substitutes, each with its own unique advantages and disadvantages. The allograft, for example, is an optimal bone graft substitute because it is abundant and free of procurement morbidity. A variety of synthetic materials, including calcium phosphate and calcium sulfate, provide structural support. Some bone morphogenic proteins are available to aid in the healing process.

Moreover, the use of synthetic bone graft substitutes is increasing, especially in the United States. Recently, OrthoPediatrics Corp. introduced a synthetic Bone Graft Substitutes called QuickPack, which is highly viscous and contains calcium phosphate cement, the mineral phase of a bone. Synthetic alternatives are expected to increase their adoption rates during the forecast period, although there are significant limitations associated with the use of artificial materials.

The osteoinductive or osteoconductive nature of bone graft materials is essential for successful use. Those substances which are osteoinductive in nature stimulate osteoprogenitor cells and initiate the formation of new bone. Osteoinductive materials are known to trigger the growth of new osteoblasts, which promotes quicker integration of the graft. Similarly, osteoconductive materials are better for promoting the development of new bone.

As the demand for spine and joint fusion surgeries rises, the need for bone substitutes is rising. Currently, there are not enough donors for allogeneic bone, which means the availability of artificial bone substitutes is essential. The use of these implants increases the risk of infections, so patients should be informed about the risks associated with the procedure and its use. Infection at the transplant site is also a contraindication to using allografts.

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